DO NO HARM
Mistakes are unacceptable when one is dealing with matters of Life and Death. Getting into a battle with a villain risks not only the lives of those involved, but those of anyone within range of their weapons. Remember: With great power comes great responsibility!
Non-lethal means of apprehending a villain provide an essential safety-margin, although even non-lethal techniques can sometimes result in injury or death. Sound judgment is always essential to prevent tragedy.
Unless a Hero chances upon a major crime in progress, careful research and planning are essential to any action to be taken. Poor research and planning could result in trying to apprehend undercover law-enforcement officers and other undesirable outcomes.
Although it may be tempting to pursue petty criminals due to the ease with which they can be found, in many cases it does not truly serve the cause of justice, nor is it worth the risk.
Apprehending prostitutes saves no lives, protects no property, and does not significantly advance the cause of justice.
Apprehending casual drug users is also of limited value to society.
When confronted by an essentially victimless crime, the appropriate response is, if anything, a warning or stern lecture, not trying to physically apprehend them.